09h20-09h30

Introduction

Annabel BERTHON (Research Working Group Coordinator) - Luisa BRUNO (FIRENDO Scientific Project Officer)

09h30-9h55

Overview of Organoids

Laurent POULAIN - Audrey FERRAND (RIBBON Consortium – National Network for Organoid Production and Biobanking)

9h55 - 10h20

Establishment of Fetal Thyroid Organoids as a Model for Thyroid Development

Dulanjalee KARIYAWASAM (MCU-PH, INSERM U1016 - Équipe Lehuen / Beltrand; Service d'Endocrinologie, gynécologie, diabétologie pédiatriques - hôpital universitaire Necker - Enfants Malades)

10h20-10h45

Pituitary Organoids

Pauline ROMANET (MCU-PH, Aix Marseille Université - INSERM - MMG UMR 1251 - APHM - La Timone University Hospital - Laboratory of Molecular Biology GEnOPé, Marseille)

11h05 - 11h30

Adrenocortical Organoids: Recapitulating Development and Modelling Tumours

Lucas BOUYS (Postdoctoral Researcher, MRC Laboratory of Medical Sciences – Imperial College London)

11h30 - 11h55

Organs and Organoids-on-a-Chip: Applications to Type 1 Diabetes

Emily TUBBS (Researcher, CEA - Université Grenoble Alpes)

11h55 - 12h20

Testicular Organoids and Animal Models: Where Do We Stand?

Nathalie BEAUJEAN / Ingrid PLOTTON (DR/ PUPH, INRAE - Unité 1208; médecine et biologie reproduction - HCL Unité 1208)

12h20 - 12h45

Developing 3D Organoids to Understand the Mechanisms of Human Gonad Formation and Its Pathologies

Anu BASHAMBOO (Researcher, Institut Pasteur – Unité de Génétique du développement humain)

14h15 - 14h35

Use of SGLT2 Inhibitors in Patients with Monogenic Diabetes

Estelle AUDRAIN (CCU-AH, AP-HP - Hôpital Pitié-Salpêtrière - Service de Diabétologie)

14h35 - 14h55

McCune-Albright Syndrome: Diagnostic Challenges of a Mosaic Disorder

Camille GIANNETTI  (Resident Physician, Laboratoire de Biologie Molécualire GEnOPé; Assistance-Publique des Hôpitaux de Marseille AP-HM)

14h55 - 15h15

Development of an Adrenal Cell Model from Human Induced Pluripotent Stem Cells (hiPSCs) to Validate Novel Variants

Clement JANOT / Florence ROUCHER ( MCU-PH / PHU, Laboratoire de Biochimie Biologie Moléculaire - Unité Médicale de Biologie Endocrinienne - Hospices Civils de Lyon; Faculté de Médecine Lyon Est - Lyon 1 Université; Inserm - Institut Cellules Souche et Cerveau, Groupe Plateforme StemGam)

15h15 - 15h35

When the Genome Doesn’t Tell the Whole Story: CRISPR Reveals the Function of APOB Variants in Hypobetalipoproteinemia

Mathilde DI FILIPPO (PH, Hospices Civils de Lyon)

15h35 - 15h55

AM2P: Assessment of Prognosis and Quality of Life in Patients Hospitalized for Early-Onset Anorexia Nervosa

Manon STUDER / Coline STORDEUR (Child and Adolescent Psychiatry Resident/ PH, Service de Psychiatrie de l'Enfant et de l'Adolescent - Centre d'Excellence InovAND)

15h55 - 16h15

Genome 2025 and Pituitary Deficiency: What Can We Expect?

Karine AOUCHICHE (PH, AP-HM - Hôpital de la Timone Enfants - Service de Pédiatrie multidisciplinaire)

16h35 - 16h50

EndoCush ERN: A European Network Investigating Non-Hormonal Biomarkers of Glucocorticoid Excess and Its Complications

Guillaume ASSIE (Professor, Endocrinologie Hôpital Cochin APHP; Université Paris Cité Inserm Institut Cochin; chaire IA Santé UPC)

16h50 - 17h05

The Role of Androgens in Sexual Dimorphism of the Mouse Adrenal Gland: Understanding the Female Predominance of Adrenocortical Disorders

Elliot WEST (PhD student, iGReD - Institut de Génétique, Reproduction et Développement - Université Clermont Auvergne)

17h05 - 17h20

The Clinical Usefulness of the Trouillas Classification: 2b or Not 2b?

Anna CARRETTI (Doctor, Hospices Civils de Lyon ; Sapienza University of Rome Department of Experimental Medicine)